Choosing the right location is a critical decision for businesses in the UK and Ireland considering expansion into the United States. The US is a vast and competitive market, and selecting a base that offers strong infrastructure, business-friendly policies, skilled talent, and strategic advantages can be the difference between success and struggle.

Enter Pennsylvania, a state rapidly emerging as one of the most compelling destinations for international trade and investment. Whether you’re a manufacturer, life sciences innovator, technology disruptor, or agri-food exporter, Pennsylvania provides the ideal environment for UK and Irish businesses looking to establish a foothold in the US.

A Gateway to the US Market

Located in the heart of the US Northeast, Pennsylvania offers direct access to 40% of the US population within a day’s drive. With major hubs like New York City, Washington D.C., and Boston nearby, the state is a strategic launching pad for businesses looking to reach key commercial and consumer markets.

Pennsylvania boasts an unrivalled transportation network, including:

• 6 international airports facilitating global trade and logistics
• Three major ports providing direct shipping access
• Over 120,000 miles of highways connecting key distribution centres
• The highest number of operating railroads in the US

For companies that rely on seamless supply chain logistics, Pennsylvania is perfectly positioned to help businesses move products efficiently and cost-effectively across North America.

A Thriving Business Environment

Unlike some US states focusing on high-cost, high-tax economies, Pennsylvania balances affordability and opportunity. Businesses benefit from:

• Lower operational costs than neighbouring states like New York and New Jersey
• Pro-business tax incentives, including funding for international investors
• A diverse and skilled workforce, including top-tier graduates from the state’s universities
• Strong government support for foreign direct investment (FDI), with tailored assistance for UK and Irish businesses

Industry Strengths That Match UK & Ireland Expertise

One of Pennsylvania’s biggest strengths is its sector diversity. The state is home to:

• Life Sciences & Pharmaceuticals – Home to GSK, Merck, and a fast-growing biotech ecosystem
• Advanced Manufacturing – A $116 billion industry with expertise in aerospace, robotics, and industrial technology
• Technology & AI – A federally designated tech hub for automation, cybersecurity, and semiconductors
• Energy & Sustainability – A leader in nuclear, natural gas, hydrogen, and renewables
• Food & Agri-Food Processing – A $38 billion sector, supporting food exports across the US

This alignment makes Pennsylvania an ideal match for UK and Irish businesses seeking to expand into industries where they already excel.

Why Now? The Opportunity for UK & Irish Businesses

Pennsylvania is making serious moves to attract international businesses with new investment incentives, infrastructure funding, and a commitment to workforce development. The state has already secured billions in private investment, and UK & Irish firms are in a prime position to benefit.

If you’re considering expanding to the US, now is the time to explore Pennsylvania. Over the coming weeks, we’ll explore specific sector opportunities, funding incentives, and real-world success stories that demonstrate why Pennsylvania is the ideal destination for UK and Irish business success.